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Symbol
Name
ID

Il27
interleukin 27
MGI:2384409

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Asthma
Disease(s) Associated with IL27	Asthma
asthma

Mouse Phenotypes		abnormal CD4-positive T cell differentiation	increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number	decreased CD4-positive, alpha-beta memory T cell number	increased circulating interleukin-12b level	increased susceptibility to type IV hypersensitivity reaction	increased interferon-gamma secretion	increased susceptibility to experimental autoimmune encephalomyelitis	increased susceptibility to parasitic infection induced morbidity/mortality
Availability	Mouse Genotype	abnormal CD4-positive T cell differentiation		decreased CD4-positive, alpha-beta memory T cell number	increased circulating interleukin-12b level		increased interferon-gamma secretion
	Il27^{tm1b(EUCOMM)Wtsi}/Il27^{tm1b(EUCOMM)Wtsi}
	Il27^tm1Cua/Il27^tm1Cua
	Il27^tm1Lex/Il27^tm1Lex

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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